SCHEMBL29672225

SCHEMBL29672225

CCS(=O)(=O)c1cccnc1-c1cnc(OCC(F)(F)C(F)(F)F)cn1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DGAT1 O75907 7/20 0.35
▸ COMT P21964 1/20 0.34
▸ ALOX5AP P20292 2/20 0.33
▸ FEN1 P39748 1/20 0.33
▸ CNR2 P34972 1/20 0.32
▸ KCNH2 Q12809 1/20 0.30
▸ ATR Q13535 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22518699 1.00 DGAT1 (0.35) DGAT1COMTALOX5APFEN1CNR2
SCHEMBL22518705 0.91 DGAT1 (0.36) DGAT1COMTALOX5APFEN1CNR2
SCHEMBL22518738 0.87 ALOX5AP (0.34) DGAT1COMTALOX5APFEN1
SCHEMBL22518739 0.85 COMT (0.36) COMTALOX5APFEN1KCNH2ATR
SCHEMBL22518692 0.84 COMT (0.39) COMTALOX5APFEN1ATR
SCHEMBL22518714 0.84 EPHX2 (0.42) COMTALOX5APFEN1KCNH2
SCHEMBL17992235 0.84 CYP4F2 (0.34) DGAT1COMTALOX5APFEN1
SCHEMBL21778761 0.82 DGAT1 (0.36) DGAT1COMTCNR2KCNH2
SCHEMBL22518695 0.82 COMT (0.37) COMTALOX5APFEN1ATR
SCHEMBL22518727 0.82 ALOX5AP (0.35) COMTALOX5APFEN1KCNH2ATR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747241-A1 BENZIMIDAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-05-27 — — EP disclosed
EP-4745126-A1 PESTICIDALLY-ACTIVE 2,2-DIHALOCYCLOPROPYL COMPOUNDS Syngenta Crop Protection AG (CH) 2026-05-20 — — EP disclosed
EP-4745125-A1 PESTICIDALLY-ACTIVE 2,2-DIHALOCYCLOPROPYL COMPOUNDS Syngenta Crop Protection AG (CH) 2026-05-20 — — EP disclosed
US-20260132125-A1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2026-05-14 — — US disclosed
EP-4384523-B1 2,2-DIFLUORO-5H-[1,3]DIOXOLO[4,5-F]ISOINDOL-7-ONE DERIVATIVES AS PESTICIDES SYNGENTA CROP PROTECTION AG (CH) 2026-04-08 — — EP disclosed
US-12595266-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents SYNGENTA CROP PROTECTION AG (CH) 2026-04-07 — — US disclosed
EP-4703353-A1 PESTICIDALLY-ACTIVE 2,2-DIHALOCYCLOPROPYL COMPOUNDS Syngenta Crop Protection AG (CH) 2026-03-04 — — EP disclosed
EP-4695248-A1 PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 — — EP disclosed
EP-4695253-A1 IMIDAZO BICYCLIC DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 — — EP disclosed
EP-4694686-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2026-02-18 — — EP disclosed
WO-2023006634-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-02 — — WO disclosed
WO-2023006789-A1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-02-02 — — WO disclosed
WO-2023275116-A1 USE OF FLUAZIFOP-P-BUTYL FOR INSECT CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-01-05 — — WO disclosed
WO-2022258481-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-12-15 — — WO disclosed
WO-2022253841-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-12-08 — — WO disclosed
WO-2022219146-A2 PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-10-20 — — WO disclosed
WO-2022175318-A1 INSECT AND ACARINA PEST CONTROL SYNGENTA CROP PROTECTION AG (NL) 2022-08-25 — — WO disclosed
WO-2022157334-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-07-28 — — WO disclosed
WO-2022157188-A2 PESTICIDALLY ACTIVE HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-07-28 — — WO disclosed
WO-2022101265-A1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132125-A1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS DDT, CBR1, TUBA3C DGAT1 2105/4885COMT 675/4885ALOX5AP 4332/4885
US-12595266-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents CBR3, CBR1, CYCS DGAT1 2884/4885COMT 3484/4885ALOX5AP 2397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback