Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | VHL | P40337 | 1/20 | 0.30 |
| ▸ | ELOC | Q15369 | 1/20 | 0.30 |
| ▸ | ELOB | Q15370 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2262470 | 1.00 | NOTUM (0.48) | NOTUMIDO1MAOAMAOBLOX | |
| SCHEMBL29673151 | 0.89 | NOTUM (0.42) | NOTUMMAOAMAOBMEN1KMT2A | |
| SCHEMBL24543321 | 0.89 | NOTUM (0.42) | NOTUMMAOAMAOBMEN1KMT2A | |
| SCHEMBL2256507 | 0.79 | MEN1 (0.52) | NOTUMMEN1KMT2AL3MBTL1VHL | |
| SCHEMBL30070543 | 0.79 | MAOA (0.50) | NOTUMIDO1MAOAMAOBLOX | |
| SCHEMBL1225571 | 0.79 | MAOA (0.50) | NOTUMIDO1MAOAMAOBLOX | |
| SCHEMBL29844266 | 0.79 | MEN1 (0.52) | NOTUMMEN1KMT2AL3MBTL1VHL | |
| Methane SCHEMBL6936064 | 0.78 | MAOA (0.49) | IDO1MAOAMAOBLOXHSD17B1 | |
| SCHEMBL8366049 | 0.76 | KDM4E (0.33) | MAOAMAOBLOXMEN1KMT2A | |
| SCHEMBL22547426 | 0.76 | SIRT2 (0.35) | NOTUMMAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684628-B | Substituted indanyl imidazole compound, preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2025-06-17 | — | — | CN | disclosed |
| CN-118684628-A | Substituted indanyl imidazole compound, preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-09-24 | — | — | CN | disclosed |
| CN-114644631-A | KRAS G12C protein mutation inhibitor, preparation method thereof, pharmaceutical composition and application thereof | 上海维申医药有限公司 | 2022-06-21 | — | — | CN | disclosed |