SCHEMBL29673204

SCHEMBL29673204

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C[C@@H]1F

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ P2RX3 P56373 7/20 0.66
▸ P2RX1 P51575 4/20 0.66
▸ P2RX2 Q9UBL9 3/20 0.66
▸ P2RX4 Q99571 6/20 0.64
▸ P2RY1 P47900 5/20 0.64
▸ P2RY2 P41231 2/20 0.64
▸ SRC P12931 1/20 0.64
▸ ALDH1A1 P00352 1/20 0.64
▸ SMN1; SMN2 Q16637 1/20 0.64
▸ RNASEL Q05823 1/20 0.61
▸ MACROD2 A1Z1Q3 1/20 0.60
▸ SIRT6 Q8N6T7 1/20 0.60
▸ MACROD1 Q9BQ69 1/20 0.60
▸ TRPM2 O94759 1/20 0.60
▸ P2RX7 Q99572 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12932293 1.00 P2RX3 (0.66) P2RX3P2RX1P2RX2P2RX4P2RY1
SCHEMBL15698480 1.00 P2RX3 (0.66) P2RX3P2RX1P2RX2P2RX4P2RY1
SCHEMBL21417366 0.91 P2RY1 (0.66) P2RY1P2RY2SRCSMN1; SMN2RNASEL
SCHEMBL20324919 0.91 P2RY1 (0.66) P2RY1P2RY2SRCSMN1; SMN2RNASEL
SCHEMBL20326922 0.91 P2RY1 (0.66) P2RY1P2RY2SRCSMN1; SMN2RNASEL
SCHEMBL20224844 0.91 P2RY1 (0.66) P2RY1P2RY2SRCSMN1; SMN2RNASEL
SCHEMBL22571185 0.90 P2RY1 (0.57) P2RX3P2RX1P2RX2P2RX4P2RY1
SCHEMBL23982340 0.90 P2RX1 (0.70) P2RX3P2RX1P2RX2P2RX4P2RY1
SCHEMBL19493160 0.90 P2RX1 (0.70) P2RX3P2RX1P2RX2P2RX4P2RY1
SCHEMBL3163036 0.90 P2RX1 (0.70) P2RX3P2RX1P2RX2P2RX4P2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600957-B2 Synthesis of transcripts using VSW-3 RNA polymerase RNASYN BIOTECH. CO., LTD. (CN) 2026-04-14 — — US claimed
US-20240309447-A1 METHODS AND KITS FOR PREPARING A SAMPLE COMPRISING ONE OR MORE RNA MOLECULES FOR SEQUENCING THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-09-19 — — US claimed
US-20220220459-A1 SYNTHESIS OF TRANSCRIPTS USING VSW-3 RNA POLYMERASE RNASYN BIOTECH. CO., LTD. (CN) 2022-07-14 — — US claimed
US-12600957-B2 Synthesis of transcripts using VSW-3 RNA polymerase RNASYN BIOTECH. CO., LTD. (CN) 2026-04-14 — — US disclosed
US-20250223620-A1 NOVEL PROCESSES FOR THE PRODUCTION OF POLYNUCLEOTIDES INCLUDING OLIGONUCLEOTIDES GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2025-07-10 — — US disclosed
US-20240309447-A1 METHODS AND KITS FOR PREPARING A SAMPLE COMPRISING ONE OR MORE RNA MOLECULES FOR SEQUENCING THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-09-19 — — US disclosed
CN-116732020-A Methods for improving the efficiency and/or stability of intracellular translation of RNA molecules 中国科学院分子细胞科学卓越创新中心 2023-09-12 — — CN disclosed
WO-2023165530-A1 METHODS OF INCREASING INTRACELLULAR TRANSLATIONAL EFFICIENCY AND/OR STABILITY OF RNA MOLECULES 中国科学院分子细胞科学卓越创新中心 2023-09-07 — — WO disclosed
US-20220220459-A1 SYNTHESIS OF TRANSCRIPTS USING VSW-3 RNA POLYMERASE RNASYN BIOTECH. CO., LTD. (CN) 2022-07-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600957-B2 Synthesis of transcripts using VSW-3 RNA polymerase POLR2H, POLL, POLR2E P2RX3 822/4885P2RX1 1618/4885P2RX2 1078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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