Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | MGAM | O43451 | 4/20 | 0.74 |
| ▸ | GAA | P10253 | 4/20 | 0.74 |
| ▸ | SI | P14410 | 4/20 | 0.74 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335857 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1MGAMGAASI | |
| SCHEMBL6332523 | 0.84 | ALDH1A1 (0.72) | KDM4EALDH1A1MGAMGAASI | |
| SCHEMBL11354133 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1MGAMGAASI | |
| SCHEMBL30494547 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1MGAMGAASI | |
| SCHEMBL23084672 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1MGAMGAASI | |
| SCHEMBL11337354 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1MGAMGAASI | |
| SCHEMBL971940 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1MGAMGAASI | |
| SCHEMBL31536892 | 0.79 | ALDH1A1 (0.65) | KDM4EALDH1A1MGAMGAASI | |
| SCHEMBL23292535 | 0.79 | MGAM (0.71) | KDM4EALDH1A1MGAMGAASI | |
| SCHEMBL11326284 | 0.79 | ALDH1A1 (0.65) | KDM4EALDH1A1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661470-A | Thiadiazole urea compound or pharmaceutically acceptable salt thereof, pharmaceutical composition and application thereof | 安徽医科大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-112279845-B | Aryl or heteroaryl substituted thiadiazoles compounds and antibacterial application thereof | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | disclosed |
| CN-108947931-B | Thiazole amide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海有机化学研究所 | 2023-07-07 | — | — | CN | disclosed |
| CN-114585360-A | Methods of using the same for the treatment of epilepsy | 特维娜有限公司 | 2022-06-03 | — | — | CN | disclosed |