Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23084672 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL11335857 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL29673255 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL11025136 | 0.77 | ALDH1A1 (0.50) | KDM4EALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL971700 | 0.77 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL9313369 | 0.74 | ALDH1A1 (0.59) | KDM4EALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL968101 | 0.74 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL8046899 | 0.73 | HDAC1 (0.43) | KDM4EALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL22469017 | 0.73 | GUSB (0.46) | KDM4EALDH1A1HSD17B10HPGDRAB9A | |
| SCHEMBL970693 | 0.73 | ALDH1A1 (0.62) | KDM4EALDH1A1HSD17B10HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104292224-B | Containing replacing 1,3,4-thiophene () diazole thioether benzothiazole amide derivatives and its preparation method and application | 贵州大学 | 2016-07-06 | — | — | CN | disclosed |
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090156512-A1 | potent activity against resistant pneumococci | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1970377-A1 | LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2008-09-17 | — | — | EP | disclosed |
| US-20070184383-A1 | Photosensitive composition, photosensitive planographic printing plate material, and recording method of planographic printing plate material | KONICA MINOLTA MEDICAL & GRAPHIC, INC. | 2007-08-09 | — | — | US | disclosed |
| US-20070184383-A1 | Photosensitive composition, photosensitive planographic printing plate material, and recording method of planographic printing plate material | KONICA MINOLTA MEDICAL & GRAPHIC, INC. | 2007-08-09 | — | — | US | disclosed |
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156512-A1 | potent activity against resistant pneumococci | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NAT1, NPM1 | KDM4E 3077/4885ALDH1A1 2976/4885HSD17B10 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.