Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20587635 | 0.80 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 | |
| SCHEMBL30355446 | 0.80 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 | |
| SCHEMBL11615095 | 0.72 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 | |
| SCHEMBL11816106 | 0.70 | RAB9A (0.72) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 | |
| SCHEMBL6450847 | 0.70 | RAB9A (0.64) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 | |
| SCHEMBL6451390 | 0.69 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 | |
| SCHEMBL20533001 | 0.69 | EGFR (0.52) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 | |
| SCHEMBL5338382 | 0.69 | NPC1 (0.66) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 | |
| SCHEMBL3828355 | 0.69 | IKBKB (0.60) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 | |
| SCHEMBL4820143 | 0.69 | RAB9A (0.66) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585360-A | Methods of using the same for the treatment of epilepsy | 特维娜有限公司 | 2022-06-03 | — | — | CN | disclosed |