Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Camphor SCHEMBL31059217 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Camphor SCHEMBL16068 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Camphor SCHEMBL1151878 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Camphor SCHEMBL1712401 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Camphor SCHEMBL16582770 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Camphor SCHEMBL13248606 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Camphor SCHEMBL15542393 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| (-)-Camphor SCHEMBL1701376 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Camphor SCHEMBL2037672 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Camphor SCHEMBL285280 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345664-B2 | Process for the preparation of (S)-Netarsudil,its salts and polymorphs | Micro Labs Ltd. (IN) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345664-B2 | Process for the preparation of (S)-Netarsudil,its salts and polymorphs | VKORC1L1, CYP3A4, REN | ALDH1A1 1592/4885KMT2A 3775/4885MEN1 2484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.