Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 2/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710025 | 0.80 | PARP1 (0.39) | PARP10TDP2PARP1MAOAMAOB | |
| SCHEMBL30569562 | 0.76 | HTT (0.56) | TDP2PARP1MAOAMAOBEPHX2 | |
| SCHEMBL9710313 | 0.76 | MAOB (0.61) | MAOAMAOBHSD17B3METAP1HTT | |
| SCHEMBL8526616 | 0.75 | RYR2 (0.47) | AHRMAOAMAOBHSD17B3EPHX2 | |
| SCHEMBL299571 | 0.74 | MAOB (0.64) | CMA1AHRMAOAMAOBEPHX2 | |
| SCHEMBL30199790 | 0.72 | HTT (0.59) | CMA1AHRMAOAMAOBEPHX2 | |
| SCHEMBL1332876 | 0.72 | HTT (0.59) | CMA1AHRMAOAMAOBEPHX2 | |
| SCHEMBL30040944 | 0.72 | CMA1 (0.59) | CMA1AHRPARP10TDP2PARP1 | |
| SCHEMBL1852665 | 0.72 | CMA1 (0.59) | CMA1AHRPARP10TDP2PARP1 | |
| SCHEMBL1948977 | 0.72 | CMA1 (0.59) | CMA1AHRPARP10TDP2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4244213-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2023-09-20 | — | — | EP | disclosed |
| CN-116745288-A | Compounds and uses thereof | 福霍恩治疗公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022103899-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-19 | — | — | WO | disclosed |