Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710299 | 0.87 | AURKA (0.40) | PARP1PARP10AURKACHEK2CDK1 | |
| SCHEMBL29673299 | 0.80 | CMA1 (0.45) | PARP1PARP10HSD17B3MAOAMAOB | |
| SCHEMBL9710313 | 0.76 | MAOB (0.61) | HSD17B3MAOAMAOBALDH1A1HTT | |
| SCHEMBL30569562 | 0.76 | HTT (0.56) | PARP1MAOAMAOBEPHX2TDP2 | |
| SCHEMBL8526616 | 0.75 | RYR2 (0.47) | HSD17B3MAOAMAOBEPHX2ALDH1A1 | |
| SCHEMBL5751107 | 0.74 | MAOB (0.64) | MAOAMAOBEPHX2ALDH1A1HTT | |
| SCHEMBL31441353 | 0.72 | PARP1 (0.43) | PARP1PARP10GRM5SRD5A1TDP2 | |
| SCHEMBL31254528 | 0.72 | PARP1 (0.43) | PARP1PARP10GRM5SRD5A1TDP2 | |
| SCHEMBL10509516 | 0.69 | HTT (0.59) | MAOAMAOBEPHX2ALDH1A1HTT | |
| SCHEMBL31441323 | 0.69 | PARP1 (0.41) | PARP1PARP10GRM5SRD5A1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021668-A1 | BENZOTHIAZEPINONES AND THEIR USE AS ANTICONVULSANTS | THE BOOTS COMPANY PLC (GB) | 1992-12-10 | — | — | WO | claimed |
| WO-1992021668-A1 | BENZOTHIAZEPINONES AND THEIR USE AS ANTICONVULSANTS | THE BOOTS COMPANY PLC (GB) | 1992-12-10 | — | — | WO | disclosed |