Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120667 | 0.88 | MAOA (0.57) | MAOBMAOALMNAPDE3BPDE3A | |
| SCHEMBL15631693 | 0.76 | MAOB (1.00) | MAOBMAOALMNAPDE3BPDE3A | |
| SCHEMBL29673299 | 0.76 | CMA1 (0.45) | MAOBMAOAHTTHSD17B3METAP1 | |
| SCHEMBL9710025 | 0.76 | PARP1 (0.39) | MAOBMAOAHTTHSD17B3ALDH1A1 | |
| SCHEMBL13506283 | 0.74 | PDE3B (0.55) | MAOBMAOAPDE3BPDE3ACYP19A1 | |
| SCHEMBL5046308 | 0.73 | PDE3B (0.54) | MAOBMAOALMNAPDE3BPDE3A | |
| SCHEMBL7439499 | 0.73 | PDE3B (0.54) | MAOBMAOALMNAPDE3BPDE3A | |
| SCHEMBL30569562 | 0.73 | HTT (0.56) | MAOBMAOALMNAKDM4EHTT | |
| SCHEMBL14691719 | 0.72 | RYR2 (0.77) | MAOBMAOALMNARYR2KDM4E | |
| SCHEMBL705947 | 0.72 | MAOB (0.79) | MAOBMAOALMNAPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021668-A1 | BENZOTHIAZEPINONES AND THEIR USE AS ANTICONVULSANTS | THE BOOTS COMPANY PLC (GB) | 1992-12-10 | — | — | WO | claimed |
| WO-1992021668-A1 | BENZOTHIAZEPINONES AND THEIR USE AS ANTICONVULSANTS | THE BOOTS COMPANY PLC (GB) | 1992-12-10 | — | — | WO | disclosed |