Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18425278 | 1.00 | KDM4E (0.44) | KDM4EMAPTSMN1; SMN2APAF1MITF | |
| SCHEMBL2911673 | 0.88 | MAPT (0.44) | KDM4EMAPTSMN1; SMN2APAF1MITF | |
| SCHEMBL4518567 | 0.81 | LMNA (0.44) | KDM4EMAPTSMN1; SMN2APAF1MITF | |
| SCHEMBL15910504 | 0.80 | KDM4E (0.50) | KDM4EMAPTSMN1; SMN2APAF1MITF | |
| SCHEMBL15944504 | 0.80 | KDM4E (0.40) | KDM4EMAPTSMN1; SMN2APAF1MITF | |
| SCHEMBL2905923 | 0.78 | KDM4E (0.49) | KDM4EMAPTSMN1; SMN2APAF1MITF | |
| SCHEMBL2913499 | 0.77 | KDM4E (0.48) | KDM4EMAPTSMN1; SMN2APAF1MITF | |
| SCHEMBL15910667 | 0.77 | PDGFRB (0.48) | KDM4EMAPTSMN1; SMN2APAF1MITF | |
| SCHEMBL20300878 | 0.77 | DYRK1A (0.47) | KDM4EMAPTSMN1; SMN2APAF1MITF | |
| SCHEMBL4530991 | 0.76 | LMNA (0.46) | KDM4EMAPTSMN1; SMN2APAF1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026066-B | Pyridine compounds useful for combating phytopathogenic fungi | 巴斯夫欧洲公司 | 2022-05-31 | — | — | CN | disclosed |