SCHEMBL29675228

SCHEMBL29675228

O=C(NCc1ccccc1)C1CCC(C(=O)NCc2ccccc2)CC1

nearest known ligand 0.86

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.86
USP2 O75604 1/20 0.86
HPGD P15428 1/20 0.86
NPSR1 Q6W5P4 2/20 0.71
MC4R P32245 1/20 0.64
HTR1A P08908 1/20 0.61
HTR1B P28222 1/20 0.61
HTR2A P28223 1/20 0.61
HTR2C P28335 1/20 0.61
HTR2B P41595 1/20 0.61
MEN1 O00255 1/20 0.61
MAPK1 P28482 1/20 0.61
KMT2A Q03164 1/20 0.61
TSHR P16473 1/20 0.61
ALOX12 P18054 1/20 0.60
MAPT P10636 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2469546 1.00 ALDH1A1 (0.86) ALDH1A1USP2HPGDNPSR1MC4R
SCHEMBL5521157 0.95 ALDH1A1 (0.78) ALDH1A1USP2HPGDNPSR1MC4R
SCHEMBL17201385 0.93 ALDH1A1 (0.76) ALDH1A1USP2HPGDNPSR1MC4R
SCHEMBL7338382 0.93 ALDH1A1 (0.76) ALDH1A1USP2HPGDNPSR1MC4R
SCHEMBL6244724 0.93 ALDH1A1 (0.93) ALDH1A1USP2HPGDNPSR1MC4R
SCHEMBL18829414 0.93 ALDH1A1 (1.00) ALDH1A1USP2HPGDNPSR1MC4R
SCHEMBL13841230 0.92 ALDH1A1 (0.73) ALDH1A1USP2HPGDNPSR1MC4R
SCHEMBL507837 0.91 ALDH1A1 (0.90) ALDH1A1USP2HPGDNPSR1MC4R
SCHEMBL2105141 0.90 ALDH1A1 (0.76) ALDH1A1USP2HPGDNPSR1MC4R
SCHEMBL8599433 0.89 ALDH1A1 (0.69) ALDH1A1USP2HPGDNPSR1MC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022149430-A1 MATERIAL FOR MOLDED PRODUCT IN CONTACT WITH HIGH-PRESSURE GAS 宇部興産株式会社 2022-07-14 WO disclosed