Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | F11 | P03951 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599432 | 1.00 | ALDH1A1 (0.69) | ALDH1A1HPGDUSP2NPSR1MEN1 | |
| Hydrochloric Acid SCHEMBL3794359 | 0.98 | ALDH1A1 (0.68) | ALDH1A1HPGDUSP2NPSR1MEN1 | |
| Hydrochloric Acid SCHEMBL8595569 | 0.98 | ALDH1A1 (0.68) | ALDH1A1HPGDUSP2NPSR1MEN1 | |
| SCHEMBL29675228 | 0.89 | ALDH1A1 (0.86) | ALDH1A1HPGDUSP2NPSR1MEN1 | |
| SCHEMBL2469546 | 0.89 | ALDH1A1 (0.86) | ALDH1A1HPGDUSP2NPSR1MEN1 | |
| SCHEMBL13714308 | 0.85 | MEN1 (0.56) | ALDH1A1HPGDUSP2MEN1KMT2A | |
| SCHEMBL15679868 | 0.85 | POLB (0.64) | ALDH1A1HPGDMEN1KMT2ATSHR | |
| SCHEMBL14428878 | 0.85 | MAPT (0.61) | ALDH1A1HPGDUSP2MAPK1 | |
| SCHEMBL5521157 | 0.84 | ALDH1A1 (0.78) | ALDH1A1HPGDUSP2NPSR1MEN1 | |
| SCHEMBL7338382 | 0.83 | ALDH1A1 (0.76) | ALDH1A1HPGDUSP2NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |