Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.55 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18766090 | 0.86 | KIF11 (0.47) | ACACBKIF11EPHX2CA1CA2 | |
| SCHEMBL27254652 | 0.84 | ACACB (0.54) | ACACBMAPT | |
| SCHEMBL256233 | 0.82 | ACACB (0.55) | ACACBALDH1A1MEN1KMT2A | |
| SCHEMBL20738675 | 0.80 | EPHX2 (0.43) | ACACBKIF11EPHX2MAPTMEN1 | |
| SCHEMBL29675909 | 0.80 | VNN1 (0.46) | ACACBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15118619 | 0.77 | ACACB (0.49) | ACACBCA1CA2ALDH1A1MAPT | |
| SCHEMBL8351698 | 0.77 | ACACB (0.49) | ACACBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5987647 | 0.76 | ACACB (0.48) | ACACBEPHX2ALDH1A1MAPTMEN1 | |
| SCHEMBL19002294 | 0.76 | KIF11 (0.52) | KIF11EPHX2CA1CA2PTPN5 | |
| SCHEMBL2815438 | 0.76 | ACACB (0.48) | ACACBEPHX2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |