Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.42 |
| ▸ | HTR3B | O95264 | 3/20 | 0.42 |
| ▸ | HTR3A | P46098 | 3/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675721 | 1.00 | PIM2 (0.45) | PIM2PIM1PRKCQMAPK1NPC1 | |
| SCHEMBL18765485 | 0.95 | HTR3E (0.46) | MAPK1NPC1RAB9AHTR3EHTR3B | |
| SCHEMBL29675364 | 0.95 | HTR3E (0.46) | MAPK1NPC1RAB9AHTR3EHTR3B | |
| SCHEMBL29675519 | 0.84 | MAPK1 (0.43) | PIM1MAPK1ACACBCHRNA7 | |
| SCHEMBL29675453 | 0.83 | SHMT2 (0.47) | MAPK1RAB9AACACBCHRNA7 | |
| SCHEMBL29675744 | 0.83 | AOC3 (0.45) | PIM2PIM1PRKCQMAPK1HTR3E | |
| SCHEMBL29675445 | 0.83 | ACACB (0.43) | MAPK1NPC1ACACBCHRNA7 | |
| SCHEMBL29676235 | 0.82 | ACACB (0.50) | MAPK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL29675627 | 0.82 | ACACB (0.50) | MAPK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23343788 | 0.82 | MAPK1 (0.45) | PRKCQMAPK1NPC1RAB9AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |