SCHEMBL296757

SCHEMBL296757

COC(C)OC.O=CCBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7927646 0.87 LMNA (0.50)
SCHEMBL713319 0.82 ALDH1A1 (0.32)
Malonaldehyde SCHEMBL8113991 0.80 ALDH1A1 (0.30)
Propionaldehyde SCHEMBL1412137 0.80 ALDH1A1 (0.53)
SCHEMBL10917295 0.78
SCHEMBL2075451 0.78
SCHEMBL483681 0.78
SCHEMBL215145 0.78
SCHEMBL263379 0.76
Hydrochloric Acid SCHEMBL10834718 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6844375-B2 4-methylene-1,3-dioxolanes as cross-linking agents DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-01-18 US claimed
US-12612415-B2 Stereoselective process for preparing substituted polycyclic pyridone SHIONOGI & CO., LTD. (JP) 2026-04-28 US disclosed
EP-3693373-B1 STEREOSELECTIVE PROCESS FOR PREPARING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES SHIONOGI & CO (JP) 2025-11-26 EP disclosed
WO-2024119440-A1 BIODEGRADABLE MULTI-BLOCK COPOLYMERS COMPRISING LINKING UNITS DERIVED FROM CYCLIC KETENE ACETAL BASF SE (DE) 2024-06-13 WO disclosed
US-11590142-B2 Oxazolidinone antibiotic compounds and process of preparation Bugworks Research, Inc. (US) 2023-02-28 US disclosed
US-20230040262-A1 STEREOSELECTIVE PROCESS FOR PREPARING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES SHIONOGI & CO., LTD. (JP) 2023-02-09 US disclosed
EP-3774790-B1 OXAZOLIDINONE ANTIBIOTIC COMPOUNDS AND PROCESS OF PREPARATION BUGWORKS RES INC (US) 2023-01-25 EP disclosed
US-11286262-B2 Stereoselective process for preparing substituted polycyclic pyridone derivatives SHIONOGI & CO., LTD. (JP) 2022-03-29 US disclosed
EP-3102195-B1 BETA-SUBSTITUTED BETA-AMINO ACIDS AND ANALOGS AS CHEMOTHERAPEUTIC AGENTS QUADRIGA BIOSCIENCES INC (US) 2021-10-06 EP disclosed
CN-113056264-A Farnesoin X receptor agonists and uses thereof 梅塔科林公司 2021-06-29 CN disclosed
US-4250175-A HYPOTENSIVE AGENTS, ANTIDEPRESSANTS PHARMACIA & UPJOHN COMPANY 1981-02-10 US disclosed
US-4250181-A HYPOTENSIVE AGENTS, ANTIDEPRESSANTS THE UPJOHN COMPANY (US) 1981-02-10 US disclosed
US-4247553-A HYPOTENSIVE AGENTS, ANTIDEPRESSANTS THE UPJOHN COMPANY (US) 1981-01-27 US disclosed
US-4207239-A HYPOTENSIVE, ANTIPSYCHOTIC THE UPJOHN COMPANY (US) 1980-06-10 US disclosed
US-4206123-A INTERMEDIATES FOR HYPOTENSIVES MCCALL JOHN M (US) 1980-06-03 US disclosed
US-4181665-A INTERMEDIATES FOR AMINO DERIVATIVES POSSESSING HYPOTENSIVE AND CENTRAL NERVOUS SYSTEM ACTIVITY THE UPJOHN COMPANY (US) 1980-01-01 US disclosed
US-4179510-A ISOCHROMANS AND 2-BENZOXEPINS THE UPJOHN COMPANY (US) 1979-12-18 US disclosed
US-4166062-A HYPOTENSIVE AGENTS, CNS, ANTIDEPRESSANTS THE UPJOHN COMPANY (US) 1979-08-28 US disclosed
US-4153612-A 2-Benzoxepins THE UPJOHN COMPANY (US) 1979-05-08 US disclosed
US-4016165-A Triazino benzodiazepines THE UPJOHN COMPANY (US) 1977-04-05 US disclosed