Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21760239 | 0.84 | ALDH1A1 (0.52) | FBP1ALDH1A1 | |
| SCHEMBL20319855 | 0.82 | KMT2A (0.58) | KMT2APSIP1HDAC3HDAC1HDAC2 | |
| SCHEMBL1899410 | 0.81 | NPSR1 (0.57) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13039575 | 0.78 | HDAC1 (0.51) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19277486 | 0.76 | PSIP1 (0.52) | NAMPTPSIP1ALDH1A1GAA | |
| SCHEMBL31192532 | 0.76 | PSIP1 (0.52) | NAMPTPSIP1ALDH1A1GAA | |
| SCHEMBL10066425 | 0.76 | PSIP1 (0.56) | FBP1PSIP1ALDH1A1GAAMAPK1 | |
| SCHEMBL167735 | 0.76 | PSIP1 (0.52) | PSIP1ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL16880298 | 0.76 | PSIP1 (0.47) | NAMPTPSIP1ALDH1A1GAARORC | |
| SCHEMBL4341722 | 0.75 | CYP1A2 (0.58) | KMT2AFBP1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |