Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903558 | 1.00 | NPSR1 (0.50) | NPSR1ALDH1A1KMT2AHPGDHDAC1 | |
| SCHEMBL1899410 | 0.92 | NPSR1 (0.57) | NPSR1ALDH1A1KMT2AHPGDHDAC1 | |
| SCHEMBL13039575 | 0.85 | HDAC1 (0.51) | NPSR1ALDH1A1KMT2AHPGDHDAC1 | |
| SCHEMBL4341722 | 0.85 | CYP1A2 (0.58) | NPSR1ALDH1A1KMT2AHPGDHDAC1 | |
| SCHEMBL14174608 | 0.85 | NOS1 (0.51) | NPSR1ALDH1A1KMT2AHPGDHDAC1 | |
| SCHEMBL17123631 | 0.84 | NPSR1 (0.49) | NPSR1ALDH1A1KMT2AHPGDHDAC1 | |
| SCHEMBL20825144 | 0.84 | ALDH1A1 (0.51) | NPSR1ALDH1A1KMT2AHPGDHDAC1 | |
| SCHEMBL31168314 | 0.84 | CYP1A2 (0.56) | NPSR1ALDH1A1KMT2AHPGDHDAC1 | |
| SCHEMBL4927953 | 0.84 | CYP1A2 (0.56) | NPSR1ALDH1A1KMT2AHPGDHDAC1 | |
| SCHEMBL3368486 | 0.83 | TSHR (0.59) | ALDH1A1KMT2AHPGDHDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |
| CN-114948963-B | Benzolactam compounds as protein kinase inhibitors | 大冢制药株式会社 | 2025-05-27 | — | — | CN | disclosed |
| CN-114948963-A | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-08-30 | — | — | CN | disclosed |
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | disclosed |