Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.40 |
| ▸ | WNT1 | P04628 | 6/20 | 0.40 |
| ▸ | GSK3B | P49841 | 5/20 | 0.40 |
| ▸ | CLK2 | P49760 | 3/20 | 0.40 |
| ▸ | CLK3 | P49761 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29676371 | 0.91 | CTSA (0.44) | MAPK1HRH4NPC1RAB9ADYRK1A | |
| SCHEMBL29676029 | 0.88 | PIK3CA (0.50) | MAPK1RAB9ADYRK1AWNT1GSK3B | |
| SCHEMBL29676386 | 0.86 | HRH4 (0.44) | MAPK1HRH4NPC1RAB9APANK3 | |
| SCHEMBL29675867 | 0.79 | MEN1 (0.45) | MAPK1NPC1RAB9AROCK2 | |
| SCHEMBL29676238 | 0.78 | MAPK1 (0.44) | MAPK1HRH4NPC1RAB9ADYRK1A | |
| SCHEMBL23343788 | 0.76 | MAPK1 (0.45) | MAPK1HRH4NPC1RAB9ACDK5 | |
| SCHEMBL29675755 | 0.74 | L3MBTL1 (0.38) | MAPK1NPC1RAB9AGSK3BROCK2 | |
| SCHEMBL29676253 | 0.74 | MAPK1 (0.44) | MAPK1HRH4NPC1RAB9AHRH3 | |
| SCHEMBL29675667 | 0.74 | NPC1 (0.43) | MAPK1HRH4NPC1RAB9AHRH3 | |
| SCHEMBL23343854 | 0.74 | MAPK1 (0.40) | MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |