Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963901 | 0.80 | ADRA2A (0.47) | ESR1ESR2GRIA4NR1I2ADRA2A | |
| SCHEMBL18613186 | 0.78 | ESR1 (0.48) | ESR1ESR2GRIA4 | |
| SCHEMBL10291752 | 0.76 | ESR1 (0.47) | ESR1ESR2 | |
| SCHEMBL2970816 | 0.76 | ESR1 (0.47) | ESR1ESR2GRIA4NR1I2ADRA2A | |
| SCHEMBL984302 | 0.76 | ESR1 (0.74) | ESR1ESR2 | |
| SCHEMBL24250388 | 0.76 | ESR1 (0.52) | ESR1ESR2GRIA4NR1I2ADRA2A | |
| SCHEMBL13086684 | 0.76 | ESR1 (0.47) | ESR1ESR2 | |
| SCHEMBL2976893 | 0.76 | ESR1 (0.47) | ESR1ESR2GRIA4NR1I2ADRA2A | |
| SCHEMBL19901495 | 0.76 | ESR1 (0.47) | ESR1ESR2GRIA4 | |
| SCHEMBL5428675 | 0.76 | ESR1 (0.47) | ESR1ESR2GRIA4NR1I2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763562-B2 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | AP2M1, AP1M1, PYM1 | ESR1 361/4885ESR2 790/4885GRIA4 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.