Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5426915 | 0.92 | ESR1 (0.42) | ESR1ESR2GRIA4NR1I2 | |
| SCHEMBL5420823 | 0.91 | ESR1 (0.44) | ESR1ESR2GRIA4NR1I2ADRA2A | |
| SCHEMBL2970816 | 0.81 | ESR1 (0.47) | ESR1ESR2GRIA4NR1I2ADRA2A | |
| SCHEMBL5418778 | 0.80 | ADRA2A (0.47) | ESR1ESR2GRIA4NR1I2ADRA2A | |
| SCHEMBL5437162 | 0.79 | RIPK1 (0.36) | ESR1ESR2 | |
| SCHEMBL18613186 | 0.78 | ESR1 (0.48) | ESR1ESR2GRIA4IDO1 | |
| SCHEMBL13626412 | 0.77 | LMNA (0.40) | ESR1ESR2 | |
| SCHEMBL24250388 | 0.76 | ESR1 (0.52) | ESR1ESR2GRIA4NR1I2ADRA2A | |
| SCHEMBL2976893 | 0.76 | ESR1 (0.47) | ESR1ESR2GRIA4NR1I2ADRA2A | |
| SCHEMBL13086684 | 0.76 | ESR1 (0.47) | ESR1ESR2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070218216-A1 | Light modulating material | FUJIFILM CORPORATION | 2007-09-20 | — | — | US | disclosed |