Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794151 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP2D6CYP2C19LTA4HKMT2A | |
| SCHEMBL31393609 | 0.87 | CYP1A2 (0.55) | CYP1A2CYP2D6CYP2C19LTA4HKMT2A | |
| SCHEMBL23703051 | 0.86 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C19LTA4HKMT2A | |
| SCHEMBL9830685 | 0.86 | LTA4H (0.49) | LTA4HKMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL6325880 | 0.84 | LTA4H (0.47) | CYP1A2CYP2D6CYP2C19LTA4HKMT2A | |
| SCHEMBL5939725 | 0.84 | SCN8A (0.52) | LTA4HKMT2AMEN1SLC26A6 | |
| SCHEMBL16839753 | 0.84 | CHRM2 (0.54) | CYP1A2CYP2D6CYP2C19LTA4HKMT2A | |
| SCHEMBL16839726 | 0.83 | KMT2A (0.58) | CYP1A2CYP2D6CYP2C19LTA4HKMT2A | |
| SCHEMBL549268 | 0.83 | LTA4H (0.60) | LTA4HKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL9830258 | 0.83 | MEN1 (0.61) | KMT2AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567453-A | Benzazepine analogs as inhibitors of bruton's tyrosine kinase | 渤健马萨诸塞州股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-110621670-B | Benzazepine analogs as inhibitors of bruton's tyrosine kinase | 比奥根MA公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-109096274-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2022-07-01 | — | — | CN | disclosed |