SCHEMBL549268

SCHEMBL549268

CCOC(=O)CCNCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.60
SMN1; SMN2 Q16637 1/20 0.59
PPID Q08752 1/20 0.57
TOP2A P11388 1/20 0.52
ALDH1A1 P00352 1/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
HDAC3 O15379 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
NCOR2 Q9Y618 1/20 0.49
POLB P06746 1/20 0.48
ALOX5 P09917 1/20 0.48
MAPT P10636 1/20 0.48
NAMPT P43490 1/20 0.48
ATM Q13315 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16839750 0.94 LTA4H (0.69) LTA4HSMN1; SMN2PPIDTOP2AALDH1A1
SCHEMBL16839742 0.91 LTA4H (0.55) LTA4HSMN1; SMN2PPIDTOP2AALDH1A1
SCHEMBL8851568 0.91 LTA4H (0.63) LTA4HSMN1; SMN2PPIDTOP2AALDH1A1
Hydrochloric Acid SCHEMBL28570780 0.89 LTA4H (0.62) LTA4HSMN1; SMN2PPIDTOP2AALDH1A1
SCHEMBL16839730 0.89 LTA4H (0.59) LTA4HSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL3057335 0.88 LTA4H (0.62) LTA4HSMN1; SMN2PPIDALDH1A1HDAC3
SCHEMBL16839863 0.88 LTA4H (0.65) LTA4HALDH1A1MEN1KMT2A
SCHEMBL16839644 0.87 LTA4H (0.52) LTA4HSMN1; SMN2PPIDTOP2AALDH1A1
SCHEMBL5940295 0.87 LTA4H (0.50) LTA4HSMN1; SMN2PPIDALDH1A1KMT2A
SCHEMBL16839772 0.87 SMN1; SMN2 (0.51) LTA4HSMN1; SMN2PPIDALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
WO-2021060525-A1 COMPOSITION FOR ELECTROMAGNETIC SHIELDING, SHEET FOR ELECTROMAGNETIC SHIELDING, SINTERED BODY FOR ELECTROMAGNETIC SHIELDING, AND ELECTRONIC COMPONENT DEVICE 昭和電工マテリアルズ株式会社 2021-04-01 WO claimed
EP-0449989-A1 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES Sloan-Kettering Institute For Cancer Research (US) 1991-10-09 EP claimed
WO-1990007496-A1 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1990-07-12 WO claimed
EP-3700578-B1 SYSTEMS FOR RENAL FUNCTION DETERMINATION MEDIBEACON INC (US) 2025-12-03 EP disclosed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US disclosed
US-12227501-B2 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as CSNK1 inhibitors BAYER AKTIENGESELLSCHAFT (DE) 2025-02-18 US disclosed
US-20250051320-A1 CRBN LIGANDS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-02-13 US disclosed
US-12157731-B2 EIF4E inhibitors and uses thereof PIC Therapeutics, Inc. (US) 2024-12-03 US disclosed
CN-114369052-B Synthesis method of 3-aminopyrrolidine dihydrochloride 赤峰万泽药业股份有限公司 2024-10-15 CN disclosed
WO-2024130161-A2 NOVEL CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF BIONECURE THERAPEUTICS INC (US) 2024-06-20 WO disclosed
CN-118146163-A Benzimidazole derivative and preparation method thereof 雅安职业技术学院 2024-06-07 CN disclosed
US-4925939-A 6,7-dihydropyrrol[3,4-c]pyrido[2,3-d]pyrimidine derivatives SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1990-05-15 US disclosed
US-4826984-A Heteroarotinoid compounds as anticancer agents THE BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECHANICAL COLLEGE ACTING FOR AND ON BEHALF OF OKLAHOMA STATE UNIVERSITY (US) 1989-05-02 US disclosed
US-4785003-A N-disubstituted glycine and B-amino-propionic acid derivatives having anti-ulcer activity BIOMEASURE, INC. (US) 1988-11-15 US disclosed
US-4721787-A CONDENSATION, REDUCTION, DEHYDRATION CIBA-GEIGY CORPORATION (US) 1988-01-26 US disclosed
US-4604397-A Certain benzo-(pyrano and thiopyrano)-pyridines, useful as CNS agents CIBA-GEIGY CORPORATION (US) 1986-08-05 US disclosed
US-4598067-A Antiulcer compounds BIOMEASURE, INC. (US) 1986-07-01 US disclosed
EP-0161218-A2 Benzo-(pyrano and thiopyrano)pyridines CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed
US-4012392-A ANALGESICS, MORPHINE ANTAGONISTS ACF CHEMIEFARMA N.V. (NL) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12157731-B2 EIF4E inhibitors and uses thereof EIF4E, EIF4EBP1, EIF4A1 LTA4H 4175/4885SMN1; SMN2 2186/4885PPID 1873/4885
US-20250051320-A1 CRBN LIGANDS AND USES THEREOF CRBN, CRKL, ERBB3 LTA4H 4697/4885SMN1; SMN2 701/4885PPID 2214/4885
US-12227501-B2 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as CSNK1 inhibitors CSNK1A1, CSNK1G1, CSNK1E LTA4H 3954/4885SMN1; SMN2 2465/4885PPID 2988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.