Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.62 |
| ▸ | HTR1A | P08908 | 3/20 | 0.62 |
| ▸ | DRD3 | P35462 | 3/20 | 0.62 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30073106 | 0.84 | KDM4E (0.72) | HTR7HTR1ADRD3KDM4EALOX15 | |
| SCHEMBL30073110 | 0.84 | KDM4E (0.72) | HTR7HTR1ADRD3KDM4EALOX15 | |
| SCHEMBL4632555 | 0.83 | PARP2 (0.56) | HTR7HTR1ADRD3PARP2PARP1 | |
| SCHEMBL15908686 | 0.80 | PRMT5 (0.70) | — | |
| SCHEMBL15908693 | 0.80 | PRMT5 (0.70) | — | |
| SCHEMBL15908697 | 0.80 | PRMT5 (0.70) | — | |
| SCHEMBL4795468 | 0.79 | PARP2 (0.49) | HTR7HTR1ADRD3PARP2PARP1 | |
| SCHEMBL16868889 | 0.78 | DRD2 (0.55) | HTR7HTR1ADRD3KDM4EALOX15 | |
| SCHEMBL30073167 | 0.77 | KDM4E (0.49) | HTR7HTR1ADRD3KDM4EALOX15 | |
| SCHEMBL7983132 | 0.77 | HTR7 (1.00) | HTR7HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114948963-B | Benzolactam compounds as protein kinase inhibitors | 大冢制药株式会社 | 2025-05-27 | — | — | CN | disclosed |
| CN-114948963-A | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-08-30 | — | — | CN | disclosed |
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | disclosed |