Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.44 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29918332 | 0.86 | ALOX15 (0.52) | MAPK1PLA2G10PLA2G5 | |
| SCHEMBL23099758 | 0.85 | AOC3 (0.55) | DRD3DRD2DRD4AOC3DRD1 | |
| SCHEMBL30530722 | 0.83 | ITGB3 (0.53) | AOC3ITGB3ITGA2B | |
| SCHEMBL25363440 | 0.83 | ITGB3 (0.53) | AOC3ITGB3ITGA2B | |
| SCHEMBL4070429 | 0.83 | AOC3 (0.56) | AOC3 | |
| SCHEMBL30530638 | 0.83 | AOC3 (0.48) | MAPK1AOC3ITGB3ITGA2B | |
| SCHEMBL25362979 | 0.83 | AOC3 (0.48) | MAPK1AOC3ITGB3ITGA2B | |
| SCHEMBL18765758 | 0.83 | MAPK1 (0.49) | MAPK1AOC3ITGB3ITGA2B | |
| SCHEMBL29676865 | 0.83 | MAPK1 (0.49) | MAPK1AOC3ITGB3ITGA2B | |
| SCHEMBL19852020 | 0.80 | KDM4E (0.47) | DRD3DRD2DRD4DRD1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | disclosed |