Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 6/20 | 0.39 |
| ▸ | BRAF | P15056 | 3/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Laflunimus SCHEMBL9234178 | 1.00 | DHODH (0.67) | DHODHLMNAKDRBRAFUSP30 | |
| Laflunimus SCHEMBL21132 | 1.00 | DHODH (0.67) | DHODHLMNAKDRBRAFUSP30 | |
| Laflunimus SCHEMBL22908 | 1.00 | DHODH (0.67) | DHODHLMNAKDRBRAFUSP30 | |
| SCHEMBL17100730 | 0.86 | DHODH (0.49) | DHODHKDRBRAFUSP30EPHX2 | |
| SCHEMBL21539519 | 0.86 | DHODH (0.49) | DHODHKDRBRAFUSP30EPHX2 | |
| SCHEMBL15196662 | 0.86 | DHODH (0.62) | DHODHLMNAGAATP53MAPT | |
| SCHEMBL8717137 | 0.84 | DHODH (0.66) | DHODHLMNAGAATHRB | |
| SCHEMBL8717143 | 0.84 | DHODH (0.66) | DHODHLMNAGAATHRB | |
| SCHEMBL16274172 | 0.82 | DHODH (0.58) | DHODHGAATP53MAPTTHRB | |
| SCHEMBL28236310 | 0.81 | DHODH (0.49) | DHODHLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551488-A | Nanoparticle compositions | 艾格埃克斯制药有限公司 | 2022-12-30 | — | — | CN | claimed |
| US-11911356-B2 | Regulation of mutant TERT by BRAF V600E/map kinase pathway through FOS/GABP in human cancer | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-02-27 | — | — | US | disclosed |
| EP-4171522-A1 | NANOPARTICULATE COMPOSITION | Algiax Pharmaceuticals GmbH (DE) | 2023-05-03 | — | — | EP | disclosed |
| CN-115551488-A | Nanoparticle compositions | 艾格埃克斯制药有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115551488-A | Nanoparticle compositions | 艾格埃克斯制药有限公司 | 2022-12-30 | — | — | CN | disclosed |
| US-11338552-B2 | Composite materials, vehicle applications and methods thereof | PRODUCTIVE RESEARCH LLC (US) | 2022-05-24 | — | — | US | disclosed |