Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.69 |
| ▸ | GRN | P28799 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18762452 | 0.84 | GRN (0.58) | NAALAD2GRNSORT1ALDH1A1HSD17B10 | |
| SCHEMBL18762450 | 0.84 | GRN (0.58) | NAALAD2GRNSORT1ALDH1A1HSD17B10 | |
| SCHEMBL29678076 | 0.81 | MAPT (0.51) | NAALAD2MAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL16856563 | 0.81 | PIN1 (0.57) | MAPTALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL20204233 | 0.81 | PIN1 (0.57) | MAPTALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL28625198 | 0.78 | KMT2A (0.47) | NAALAD2GRNSORT1MAPTALDH1A1 | |
| SCHEMBL17021900 | 0.77 | PLA2G2C (0.43) | NAALAD2GRNSORT1ALDH1A1LMNA | |
| SCHEMBL17018451 | 0.77 | PPARA (0.54) | MAPTALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL20415885 | 0.76 | GRN (0.47) | GRNSORT1MAPTALDH1A1HSD17B10 | |
| SCHEMBL29677574 | 0.76 | NAALAD2 (0.40) | NAALAD2GRNSORT1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359414-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | Lycia Therapeutics, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| EP-4274619-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | Lycia Therapeutics, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022272307-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | LYCIA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022150721-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | LYCIA THERAPEUTICS, INC. (US) | 2022-07-14 | — | — | WO | disclosed |