Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30097269 | 0.86 | NAALAD2 (0.35) | NAALAD2 | |
| SCHEMBL29677931 | 0.81 | DDAH1 (0.43) | NAALAD2DDAH1MEN1KMT2AMAPT | |
| SCHEMBL24629285 | 0.77 | CAPN1 (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29677972 | 0.76 | NAALAD2 (0.69) | NAALAD2GRNSORT1MEN1KMT2A | |
| SCHEMBL23789774 | 0.74 | TDP1 (0.39) | PLK1ADORA1MEN1KMT2ABCHE | |
| SCHEMBL19451119 | 0.74 | TDP1 (0.39) | PLK1ADORA1MEN1KMT2ABCHE | |
| SCHEMBL24810240 | 0.72 | CA1 (0.45) | PLK1MEN1KMT2A | |
| SCHEMBL18237306 | 0.72 | LTA4H (0.39) | PLK1MEN1KMT2AALDH1A1 | |
| SCHEMBL30097254 | 0.72 | LTA4H (0.39) | PLK1MEN1KMT2AALDH1A1 | |
| SCHEMBL19451386 | 0.71 | TDP1 (0.45) | MEN1KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250127913-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | LYCIA THERAPEUTICS, INC. | 2025-04-24 | — | — | US | disclosed |
| US-20240165250-A1 | Bifunctional Folate Receptor Binding Compounds | LYCIA THERAPEUTICS, INC. | 2024-05-23 | — | — | US | disclosed |
| EP-4359414-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | Lycia Therapeutics, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| EP-4274619-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | Lycia Therapeutics, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022272307-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | LYCIA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022150721-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | LYCIA THERAPEUTICS, INC. (US) | 2022-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250127913-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | FOLR1, FOLR2, FOLH1 | NAALAD2 344/4885GRN 2473/4885SORT1 176/4885 |
| US-20240165250-A1 | Bifunctional Folate Receptor Binding Compounds | FOLR1, FOLR2, FOLH1 | NAALAD2 344/4885GRN 2473/4885SORT1 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.