SCHEMBL29678002

SCHEMBL29678002

C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 8/20 0.53
▸ OPRK1 P41145 10/20 0.51
▸ OPRM1 P35372 7/20 0.51
▸ ACE2 Q9BYF1 4/20 0.48
▸ OPRD1 P41143 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32679555 0.94 MAPK8 (0.50) ACEOPRK1OPRM1OPRD1
SCHEMBL11930368 0.90 OPRK1 (0.53) ACEOPRK1OPRM1ACE2OPRD1
SCHEMBL18176610 0.89 OPRK1 (0.63) OPRK1OPRM1
SCHEMBL29666821 0.89 OPRM1 (0.56) ACEOPRK1OPRM1OPRD1
SCHEMBL20363357 0.89 ACE (0.51) ACEOPRK1OPRM1ACE2OPRD1
SCHEMBL21886404 0.88 OPRK1 (0.56) ACEOPRK1OPRM1ACE2OPRD1
SCHEMBL30393094 0.87 OPRK1 (0.51) OPRK1OPRM1
SCHEMBL24360693 0.87 OPRK1 (0.66) OPRK1OPRM1
SCHEMBL31384595 0.87 NPY4R (0.60) OPRK1OPRM1
SCHEMBL31384592 0.87 NPY4R (0.60) OPRK1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584372-A1 IMMOBILIZED PROTEASES FOR ACTIVATION OF THE ZYMOGEN FORM OF TRANSGLUTAMINASE Curie Co. Inc. (US) 2025-07-16 — — EP disclosed
CN-119855902-A Immobilized protease for activating transglutaminase in zymogen form 居里公司 2025-04-18 — — CN disclosed
US-20240093162-A1 IMMOBILIZED PROTEASES FOR ACTIVATION OF THE ZYMOGEN FORM OF TRANSGLUTAMINASE CURIE CO. INC. 2024-03-21 — — US disclosed
WO-2024054236-A1 IMMOBILIZED PROTEASES FOR ACTIVATION OF THE ZYMOGEN FORM OF TRANSGLUTAMINASE CURIE CO. INC. (US) 2024-03-14 — — WO disclosed
CN-114686408-B Method for enhancing VOC family protein gene expression and improving glutamine transaminase yield 泰兴市东圣生物科技有限公司 2023-12-08 — — CN disclosed
CN-114686410-B Glutamine transaminase high-yield strain for enhancing transcription level of 1-phosphofructokinase gene and preparation and fermentation methods thereof 泰兴市东圣生物科技有限公司 2023-11-21 — — CN disclosed
CN-114686408-A Method for increasing output of glutamine transaminase by enhancing expression of VOC family protein gene 泰兴市东圣生物科技有限公司 2022-07-01 — — CN disclosed
CN-114686410-A Glutamine transaminase high-producing strain for enhancing 1-phosphofructokinase gene transcription level and preparation and fermentation methods thereof 江苏东汇生物科技有限公司 2022-07-01 — — CN disclosed
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