SCHEMBL29678404

SCHEMBL29678404

[2H]C1([2H])C(OC(C)=O)O[C@](C#C)(COC(=O)c2ccc(C)cc2)[C@H]1OC(=O)c1ccc(C)cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PRKCA P17252 3/20 0.36
▸ PRKCG P05129 1/20 0.36
▸ PRKCB P05771 1/20 0.36
▸ PRKCE Q02156 1/20 0.36
▸ PRKCD Q05655 1/20 0.36
▸ RAB9A P51151 4/20 0.35
▸ NPC1 O15118 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ HPGD P15428 2/20 0.33
▸ SCN1A P35498 1/20 0.33
▸ SCN2A Q99250 1/20 0.33
▸ SCN3A Q9NY46 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26135802 0.90 PRKCA (0.37) PRKCAPRKCGPRKCBPRKCEPRKCD
SCHEMBL18670631 0.90 PRKCA (0.37) PRKCAPRKCGPRKCBPRKCEPRKCD
SCHEMBL26129664 0.90 PRKCA (0.37) PRKCAPRKCGPRKCBPRKCEPRKCD
SCHEMBL18670633 0.90 PRKCA (0.37) PRKCAPRKCGPRKCBPRKCEPRKCD
SCHEMBL29678706 0.87 HPGD (0.37) PRKCAPRKCGPRKCBPRKCEPRKCD
SCHEMBL18670630 0.80 HPGD (0.38) PRKCAPRKCGPRKCBPRKCEPRKCD
SCHEMBL18670654 0.80 HPGD (0.38) PRKCAPRKCGPRKCBPRKCEPRKCD
SCHEMBL18670648 0.79 SCN1A (0.38) PRKCAPRKCGPRKCBPRKCEPRKCD
SCHEMBL18670646 0.79 SCN1A (0.38) PRKCAPRKCGPRKCBPRKCEPRKCD
SCHEMBL31308611 0.79 POLB (0.40) PRKCAPRKCGPRKCBPRKCEPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12370208-B2 Adenosine derivative and pharmaceutical composition comprising the same BRII BIOSCIENCES, INC. (US) 2025-07-29 — — US disclosed
US-20220288098-A1 ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME BRII BIOSCIENCES, INC. 2022-09-15 — — US disclosed
EP-4003369-A1 ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME Brii Biosciences, Inc. (US) 2022-06-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12370208-B2 Adenosine derivative and pharmaceutical composition comprising the same ADAR, ADA, ADORA2A PRKCA 1994/4885PRKCG 1840/4885PRKCB 1700/4885
US-20220288098-A1 ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ADAR, ADA, ADORA2A PRKCA 1994/4885PRKCG 1840/4885PRKCB 1700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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