Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30222457 | 1.00 | CCR2 (0.33) | CCR2CTSLCTSBNPC1MAPT | |
| SCHEMBL30396402 | 0.91 | CCR2 (0.37) | CCR2NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30222769 | 0.79 | KDM4E (0.36) | CCR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30174805 | 0.79 | KDM4E (0.36) | CCR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30192621 | 0.78 | CCR2 (0.31) | CCR2 | |
| SCHEMBL25313694 | 0.75 | FOLH1 (0.46) | CCR2 | |
| SCHEMBL25313700 | 0.75 | FOLH1 (0.46) | CCR2 | |
| SCHEMBL30403540 | 0.74 | PLAAT5 (0.46) | CTSLNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL24486583 | 0.74 | GAA (0.35) | CCR2MAPT | |
| SCHEMBL30170353 | 0.74 | GAA (0.35) | CCR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263502-A1 | SARS-COV-2 MPRO INHIBITOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2023-10-25 | — | — | EP | claimed |
| WO-2022129953-A1 | SARS-COV-2 MPRO INHIBITOR COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-06-23 | — | — | WO | claimed |
| EP-4380920-A1 | INHIBITORS FOR CORONAVIRUSES | Cocrystal Pharma, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| WO-2023014758-A1 | INHIBITORS FOR CORONAVIRUSES | COCRYSTAL PHARMA, INC. (US) | 2023-02-09 | — | — | WO | disclosed |