Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | MGAM | O43451 | 4/20 | 0.50 |
| ▸ | SI | P14410 | 4/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678756 | 0.92 | GAA (0.51) | NR3C1PGRNR3C2ARGAA | |
| SCHEMBL29678938 | 0.88 | GAA (0.50) | NR3C1PGRNR3C2ARGAA | |
| SCHEMBL29678804 | 0.86 | MAPT (0.49) | NR3C1PGRNR3C2ARGAA | |
| SCHEMBL29678752 | 0.84 | MAPT (0.52) | NR3C1PGRNR3C2ARGAA | |
| SCHEMBL945682 | 0.80 | NR3C1 (0.55) | NR3C1PGRNR3C2ARGAA | |
| SCHEMBL29678809 | 0.80 | NR3C1 (0.46) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL29679210 | 0.79 | MAPT (0.51) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL29678900 | 0.76 | NR3C1 (0.46) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL946518 | 0.75 | MEN1 (0.52) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL29678961 | 0.75 | MAPT (0.45) | NR3C1GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022131722-A1 | NOVEL INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND COMPOSITION FOR IMPROVING COGNITIVE FUNCTIONS COMPRISING SAME | (주)케이메디켐 | 2022-06-23 | — | — | WO | claimed |
| WO-2022131722-A1 | NOVEL INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND COMPOSITION FOR IMPROVING COGNITIVE FUNCTIONS COMPRISING SAME | (주)케이메디켐 | 2022-06-23 | — | — | WO | disclosed |