Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | MGAM | O43451 | 3/20 | 0.43 |
| ▸ | SI | P14410 | 3/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678756 | 0.86 | GAA (0.51) | MAPTKMT2AMEN1TDP1GAA | |
| SCHEMBL29678784 | 0.86 | NR3C1 (0.56) | MAPTKMT2AMEN1TDP1NPSR1 | |
| SCHEMBL29678752 | 0.85 | MAPT (0.52) | MAPTKMT2AMEN1TDP1NPSR1 | |
| SCHEMBL29678938 | 0.83 | GAA (0.50) | MAPTKMT2AMEN1GAAMGAM | |
| SCHEMBL29678961 | 0.79 | MAPT (0.45) | MAPTKMT2AMEN1NPSR1GAA | |
| SCHEMBL29678814 | 0.77 | MAPT (0.55) | MAPTKMT2AMEN1TDP1NPSR1 | |
| SCHEMBL29678809 | 0.77 | NR3C1 (0.46) | MAPTKMT2AMEN1NPSR1GAA | |
| SCHEMBL29679210 | 0.76 | MAPT (0.51) | MAPTKMT2AMEN1GAAMGAM | |
| SCHEMBL29678900 | 0.76 | NR3C1 (0.46) | MAPTKMT2AMEN1NPSR1GAA | |
| SCHEMBL29678902 | 0.76 | MAPT (0.51) | MAPTKMT2AMEN1TDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022131722-A1 | NOVEL INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND COMPOSITION FOR IMPROVING COGNITIVE FUNCTIONS COMPRISING SAME | (주)케이메디켐 | 2022-06-23 | — | — | WO | claimed |
| WO-2022131722-A1 | NOVEL INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND COMPOSITION FOR IMPROVING COGNITIVE FUNCTIONS COMPRISING SAME | (주)케이메디켐 | 2022-06-23 | — | — | WO | disclosed |