Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678814 | 0.90 | MAPT (0.55) | MAPTNPSR1MGAMGAASI | |
| SCHEMBL29678752 | 0.89 | MAPT (0.52) | MAPTNPSR1MGAMGAASI | |
| SCHEMBL29678778 | 0.86 | IDO1 (0.47) | MAPTNPSR1MGAMGAASI | |
| SCHEMBL29678695 | 0.81 | MAPT (0.55) | MAPTNPSR1MGAMGAASI | |
| SCHEMBL29678961 | 0.81 | MAPT (0.45) | MAPTNPSR1MGAMGAASI | |
| SCHEMBL29678900 | 0.80 | NR3C1 (0.46) | MAPTNPSR1MGAMGAASI | |
| SCHEMBL29679111 | 0.79 | MAPT (0.44) | MAPTNPSR1MGAMGAASI | |
| SCHEMBL950269 | 0.76 | MGAM (0.49) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL29678809 | 0.76 | NR3C1 (0.46) | MAPTNPSR1MGAMGAASI | |
| SCHEMBL29678804 | 0.76 | MAPT (0.49) | MAPTNPSR1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022131722-A1 | NOVEL INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND COMPOSITION FOR IMPROVING COGNITIVE FUNCTIONS COMPRISING SAME | (주)케이메디켐 | 2022-06-23 | — | — | WO | claimed |
| WO-2022131722-A1 | NOVEL INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND COMPOSITION FOR IMPROVING COGNITIVE FUNCTIONS COMPRISING SAME | (주)케이메디켐 | 2022-06-23 | — | — | WO | disclosed |