Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.74 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.59 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
| ▸ | CPB1 | P15086 | 1/20 | 0.58 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19066644 | 0.96 | FOLH1 (0.79) | FOLH1NAALAD2SIRT5CPB1CPB2 | |
| SCHEMBL2873941 | 0.86 | MME (0.63) | FOLH1NAALAD2 | |
| SCHEMBL14778231 | 0.86 | MME (0.63) | FOLH1NAALAD2 | |
| SCHEMBL14729484 | 0.85 | FOLH1 (1.00) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL18161459 | 0.85 | FOLH1 (1.00) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL18145488 | 0.85 | FOLH1 (1.00) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL19742200 | 0.85 | FOLH1 (1.00) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL31514306 | 0.85 | NAALAD2 (0.66) | FOLH1NAALAD2 | |
| SCHEMBL31514303 | 0.85 | NAALAD2 (0.66) | FOLH1NAALAD2 | |
| SCHEMBL31514298 | 0.83 | FOLH1 (0.69) | FOLH1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003959-A1 | TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER | Bayer AS (NO) | 2022-06-01 | — | — | EP | disclosed |