SCHEMBL2967940

SCHEMBL2967940

CC(C)COc1cccc(OCC(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.55
TSHR P16473 1/20 0.52
MAPK1 P28482 1/20 0.52
HIF1A Q16665 1/20 0.52
NR1H4 Q96RI1 1/20 0.49
MTNR1A P48039 3/20 0.49
MTNR1B P49286 3/20 0.49
LMNA P02545 1/20 0.48
SIRT2 Q8IXJ6 1/20 0.48
KDM4E B2RXH2 1/20 0.47
HTR1D P28221 1/20 0.46
HTR1B P28222 1/20 0.46
KAT6A Q92794 1/20 0.46
ADRB2 P07550 1/20 0.45
ADRB1 P08588 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
FOS P01100 1/20 0.44
JUN P05412 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5786398 0.92 MAPK1 (0.64) TRIM24TSHRMAPK1MTNR1AMTNR1B
SCHEMBL13647242 0.90 KDM4E (0.51) TRIM24TSHRMAPK1HIF1ANR1H4
SCHEMBL6054806 0.88 HTR1D (0.61) TRIM24NR1H4LMNASIRT2KDM4E
Ethylene SCHEMBL27542294 0.88 TP53 (0.52) TRIM24TSHRMAPK1HIF1ANR1H4
SCHEMBL3723068 0.87 ADRB2 (0.59) TRIM24ADRB2ADRB1SMN1; SMN2MAPT
SCHEMBL15383224 0.87 TRIM24 (0.47) TRIM24TSHRMAPK1HIF1ANR1H4
SCHEMBL15336466 0.87 TSHR (0.51) TRIM24TSHRHIF1A
SCHEMBL255566 0.86 USP2 (0.49) TRIM24NR1H4KAT6AHPGD
SCHEMBL4349792 0.86 MAOB (0.55) TRIM24NR1H4LMNAKDM4EMAPT
SCHEMBL3164505 0.86 CHRNB2 (0.54) TRIM24TSHRMAPK1HIF1ANR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518833-B2 Composition, film, near infrared cut filter, laminate, pattern forming method, solid image pickup element, image display device, infrared sensor, and color filter FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20210139708-A1 COMPOSITION, FILM, NEAR INFRARED CUT FILTER, LAMINATE, PATTERN FORMING METHOD, SOLID IMAGE PICKUP ELEMENT, IMAGE DISPLAY DEVICE, INFRARED SENSOR, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2021-05-13 US disclosed
US-20210071032-A1 ACTINIC RADIATION-CURABLE URETHANE/UREA-CONTAINING AEROSPACE COATINGS AND SEALANTS PRC-DESOTO INTERNATIONAL, INC. 2021-03-11 US disclosed
US-10883016-B2 Actinic radiation-curable urethane/urea-containing aerospace coatings and sealants PRC-DESOTO INTERNATIONAL, INC. (US) 2021-01-05 US disclosed
US-20190169465-A1 ACTINIC RADIATION-CURABLE URETHANE/UREA-CONTAINING AEROSPACE COATINGS AND SEALANTS PRC-DESOTO INTERNATIONAL, INC. (US) 2019-06-06 US disclosed
WO-2018031532-A1 ACTINIC RADIATION-CURABLE URETHANE/UREA-CONTAINING AEROSPACE COATINGS AND SEALANTS PRC-DESOTO INTERNATIONAL, INC. (US) 2018-02-15 WO disclosed
US-9193827-B2 Poly(beta-amino alcohols), their preparation, and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-11-24 US disclosed
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF RNS CO.,LTD. (KR) 2015-10-08 US disclosed
US-20130302401-A1 POLY(BETA-AMINO ALCOHOLS), THEIR PREPARATION, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-11-14 US disclosed
EP-1445249-B1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO LTD (JP) 2012-11-07 EP disclosed
US-7772285-B2 Benzophenone derivatives or salts thereof TOYAMA CHEMICAL CO., LTD. (JP) 2010-08-10 US disclosed
US-20090118169-A1 NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-05-07 US disclosed
US-7314888-B1 Compounds and medicinal use thereof TOYAMA CHEMICAL CO., LTD. (JP) 2008-01-01 US disclosed
US-20050113400-A1 Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo SHUNICHI SHIOZAWA (JP) 2005-05-26 US disclosed
EP-1445249-A1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2004-08-11 EP disclosed
EP-1127869-A1 NOVEL COMPOUNDS AND MEDICINAL USE THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2001-08-29 EP disclosed
US-4125512-A RESORCINOL DONOR, FORMALDEHYDE DONOR, CALCIUM SILICATE, GROUP 2A OR 3A METAL OXIDE BAYER AKTIENGESELLSCHAFT (DE) 1978-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF HRH3, CBR3, H1-0 TRIM24 2741/4885TSHR 4026/4885MAPK1 1198/4885
US-20090118169-A1 NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF SP1, AP1G1, AP1M1 TRIM24 1176/4885TSHR 4233/4885MAPK1 763/4885
US-20050113400-A1 Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo SP1, AP1G1, JUN TRIM24 245/4885TSHR 1002/4885MAPK1 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.