Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.65 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.65 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.65 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.64 |
| ▸ | KDM1A | O60341 | 3/20 | 0.53 |
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.53 |
| ▸ | NMUR1 | Q9HB89 | 5/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 5/20 | 0.51 |
| ▸ | NPY4R | P50391 | 5/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.51 |
| ▸ | NPY1R | P25929 | 3/20 | 0.51 |
| ▸ | CALCA | P06881 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.50 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29679821 | 0.96 | MAPK8 (0.63) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL29679870 | 0.92 | MAPK8 (0.54) | MAPK8MAPK9MAPK10KEAP1NMUR2 | |
| SCHEMBL30607414 | 0.89 | MAPK8 (0.64) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL31401835 | 0.88 | KEAP1 (0.65) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL30726561 | 0.87 | KEAP1 (0.68) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL29376375 | 0.87 | KEAP1 (0.60) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL30436616 | 0.87 | MAPK8 (0.69) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL30712941 | 0.86 | MAPK8 (0.73) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL30906522 | 0.86 | MAPK8 (0.67) | MAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL30429680 | 0.86 | EP300 (0.61) | MAPK8MAPK9MAPK10KEAP1NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022069704-A2 | IMMUNODIAGNOSTIC AGENTS AND METHODS FOR THE DETECTION AND DIFFERENTIATION OF CORONAVIRUS INFECTIONS | INSTITUT FÜR MOLEKULARE DIAGNOSTIK UND BIOANALYTIK (IMDB) GGMBH (DE) | 2022-04-07 | — | — | WO | disclosed |