SCHEMBL30726561

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	KEAP1	Q14145	2/20	0.68

▸	MAPK8	P45983	1/20	0.62

▸	MAPK9	P45984	1/20	0.62

▸	MAPK10	P53779	1/20	0.62

▸	PTH1R	Q03431	4/20	0.56

▸	GLP1R	P43220	5/20	0.52

▸	KDM1A	O60341	2/20	0.51

▸	VIPR1	P32241	2/20	0.51

▸	VIPR2	P41587	1/20	0.51

▸	REN	P00797	1/20	0.51

▸	ECE1	P42892	1/20	0.50

▸	MUS81	Q96NY9	1/20	0.50

▸	KRAS	P01116	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30906548	0.97	KEAP1 (0.72)	KEAP1MAPK8MAPK9MAPK10PTH1R
SCHEMBL30906421	0.97	KEAP1 (0.68)	KEAP1MAPK8MAPK9MAPK10PTH1R
SCHEMBL30906522	0.96	MAPK8 (0.67)	KEAP1MAPK8MAPK9MAPK10PTH1R
SCHEMBL31027109	0.95	KEAP1 (0.64)	KEAP1MAPK8MAPK9MAPK10PTH1R
SCHEMBL30906447	0.93	KEAP1 (0.66)	KEAP1MAPK8MAPK9MAPK10PTH1R
SCHEMBL30906440	0.92	KEAP1 (0.68)	KEAP1MAPK8MAPK9MAPK10PTH1R
SCHEMBL31462013	0.91	MAPK8 (0.59)	KEAP1MAPK8MAPK9MAPK10PTH1R
SCHEMBL31462011	0.91	MAPK8 (0.59)	KEAP1MAPK8MAPK9MAPK10PTH1R
SCHEMBL31401835	0.90	KEAP1 (0.65)	KEAP1MAPK8MAPK9MAPK10PTH1R
SCHEMBL30950134	0.90	KEAP1 (0.66)	KEAP1MAPK8MAPK9MAPK10PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4598964-A2	ANTI-IGE ANTIBODIES	Abwiz Bio, Inc. (US)	2025-08-13	—	—	EP	disclosed
US-20240182599-A1	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC.	2024-06-06	—	—	US	disclosed
WO-2024076785-A2	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC. (US)	2024-04-11	—	—	WO	disclosed
WO-2024020063-A2	ANTI-HRF ANTIBODIES	LA JOLLA INSTITUTE FOR IMMUNOLOGY (US)	2024-01-25	—	—	WO	disclosed