Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.57 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.57 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23142266 | 1.00 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL10340684 | 1.00 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8148728 | 1.00 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL10340553 | 1.00 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8145657 | 1.00 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28201827 | 0.98 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28238714 | 0.98 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL4272468 | 0.98 | GPR84 (0.56) | GPR84FFAR1MAPTLCKPPARD | |
| Water SCHEMBL28288656 | 0.96 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL2309562 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567443-A | biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2018-01-09 | — | — | CN | claimed |
| CN-116033899-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-04-28 | — | — | CN | disclosed |
| CN-105308048-B | Substituted 2-azabicyclic compounds and their use as orexin receptor modulators | 詹森药业有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-109206417-A | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-109153680-A | Novel 4-aminopyrazolo [3,4-d ] pyrimidinylazabicyclo derivatives and pharmaceutical compositions containing the same | 株式会社大熊制药 | 2019-01-04 | — | — | CN | disclosed |
| CN-108864093-A | Substituted 2- Azabicyclic compound and their purposes as orexin receptor regulator | 詹森药业有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-104768951-B | Pungent 7 ketone derivatives of 1,6 diazabicyclos [3,2,1] and its purposes in bacterium infection is treated | 沃克哈特有限公司 | 2018-03-23 | — | — | CN | disclosed |
| CN-107567443-A | biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2018-01-09 | — | — | CN | disclosed |
| CN-107108566-A | Substitution 2 Azabicyclic compounds and they as orexin receptor conditioning agent purposes | 詹森药业有限公司 | 2017-08-29 | — | — | CN | disclosed |
| EP-1501897-B1 | METHOD FOR THE PRODUCTION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIIMIDES AND PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIANHYDRIDE AND NAPHTALENE-1,8-DICARBOXYLIMIDES | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |
| EP-0873342-A1 | 1,7-DIAROXY- OR 1,7-DIARYLTHIO-SUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND THEIR DIANHYDRIDES AND DIIMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| EP-0869959-A1 | 1,7-DISUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND DIANHYDRIDES AND DIIMIDES OF SAID ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-14 | — | — | EP | disclosed |
| EP-0647137-A4 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF. | UNIV CALIFORNIA WEBER ECKARD (US) | 1998-09-16 | — | — | EP | disclosed |
| CN-1163910-A | Corrosion-inhibiting coating composition for metals | CIBA GEIGY AG (CH) | 1997-11-05 | — | — | CN | disclosed |
| WO-1997022608-A1 | 1,7-DISUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND DIANHYDRIDES AND DIIMIDES OF SAID ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-26 | — | — | WO | disclosed |
| WO-1997022607-A1 | 1,7-DIAROXY- OR 1,7-DIARYLTHIO-SUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND THEIR DIANHYDRIDES AND DIIMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-26 | — | — | WO | disclosed |
| EP-0732942-A1 | ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS | ACEA PHARMACEUTICALS, INC. (US) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995012417-A1 | ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS | ACEA PHARMACEUTICALS, INC. (US) | 1995-05-11 | — | — | WO | disclosed |
| EP-0647137-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-12 | — | — | EP | disclosed |
| US-4386013-A | COMPOSITE OF RHODIUM METAL OR COMPOUND AND A TETRAVALENT COORDINATING COMPOUND | OCCIDENTAL RESEARCH CORPORATION (US) | 1983-05-31 | — | — | US | disclosed |