SCHEMBL8145657

SCHEMBL8145657

[CH2]C(CCCCCCCC)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.59
FFAR1 O14842 2/20 0.59
MAPT P10636 1/20 0.57
LCK P06239 1/20 0.57
PPARD Q03181 1/20 0.57
ZDHHC20 Q5W0Z9 1/20 0.57
ZDHHC2 Q9UIJ5 1/20 0.57
ACE2 Q9BYF1 1/20 0.53
GRIK1 P39086 2/20 0.48
GRIK2 Q13002 2/20 0.48
FFAR4 Q5NUL3 1/20 0.48
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
LAP3 P28838 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23142266 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL10340684 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8148728 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL296798 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL10340553 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL28201827 0.98 GPR84 (0.57) GPR84FFAR1MAPTLCKPPARD
SCHEMBL28238714 0.98 GPR84 (0.57) GPR84FFAR1MAPTLCKPPARD
SCHEMBL4272468 0.98 GPR84 (0.56) GPR84FFAR1MAPTLCKPPARD
Water SCHEMBL28288656 0.96 GPR84 (0.55) GPR84FFAR1MAPTLCKPPARD
SCHEMBL2309562 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116234798-A Sulfamate derivative compounds for the treatment or alleviation of psychotic disorders 生物药品解决方案有限公司 2023-06-06 CN disclosed
CN-106507667-B Sulfamate derivatives for the prevention or treatment of epilepsy 比皮艾思药物研发有限公司 2020-01-24 CN disclosed
CN-107847768-A Method for preparing a composition comprising multiple populations of microcapsules 宝洁公司 2018-03-27 CN disclosed
CN-107835681-A Composition comprising a plurality of populations of microcapsules comprising perfume 宝洁公司 2018-03-23 CN disclosed
CN-107809994-A Include the composition of multiple microcapsules colonies 宝洁公司 2018-03-16 CN disclosed
CN-106507667-A For preventing or treating the sulfamate derivatives of epilepsy 比皮艾思药物研发有限公司 2017-03-15 CN disclosed
EP-0732942-A4 ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS COCENSYS INC (US) 2000-03-22 EP disclosed
EP-0647137-A4 GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF. UNIV CALIFORNIA WEBER ECKARD (US) 1998-09-16 EP disclosed
EP-0732942-A1 ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS ACEA PHARMACEUTICALS, INC. (US) 1996-09-25 EP disclosed
WO-1995012417-A1 ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS ACEA PHARMACEUTICALS, INC. (US) 1995-05-11 WO disclosed
EP-0647137-A1 GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-04-12 EP disclosed
EP-0151189-B1 ANTINEOPLASTIC AGENT TEIJIN LIMITED (JP) 1990-01-31 EP disclosed
US-4757139-A 5-fluoro-2'-deoxyuridine derivative, processes for preparing same and antitumor composition containing the same TEIJIN LIMITED (JP) 1988-07-12 US disclosed
EP-0151189-A1 ANTINEOPLASTIC AGENT TEIJIN LIMITED (JP) 1985-08-14 EP disclosed