Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 2/20 | 0.64 |
| ▸ | JUN | P05412 | 2/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2968397 | 0.89 | FOS (0.51) | FOSJUNNR1H4MAPTALDH1A1 | |
| SCHEMBL31191805 | 0.78 | FOS (1.00) | FOSJUNNR1H4MAPTALDH1A1 | |
| SCHEMBL1527292 | 0.78 | FOS (1.00) | FOSJUNNR1H4MAPTALDH1A1 | |
| SCHEMBL27911613 | 0.75 | FOS (0.61) | FOSJUNNR1H4MAPTALDH1A1 | |
| SCHEMBL13442883 | 0.75 | FOS (0.82) | FOSJUNNR1H4MAPTALDH1A1 | |
| SCHEMBL27594611 | 0.74 | FOS (0.59) | FOSJUNNR1H4MAPTALDH1A1 | |
| SCHEMBL2967371 | 0.73 | JUN (0.48) | FOSJUNMAPTALDH1A1KDM4E | |
| SCHEMBL2967945 | 0.73 | JUN (0.47) | FOSJUNLMNAHPGDLTB4R | |
| SCHEMBL2965164 | 0.72 | JUN (0.47) | FOSJUNALDH1A1LMNAHPGD | |
| SCHEMBL2969937 | 0.71 | JUN (0.43) | FOSJUNMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101402562-B | Novel benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD | 2013-07-31 | — | — | CN | disclosed |
| EP-1445249-B1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| CN-101054345-B | Novel bensophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD | 2010-06-02 | — | — | CN | disclosed |
| CN-1602291-B | Novel benzophenone derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2010-05-12 | — | — | CN | disclosed |
| CN-101402562-A | Novel benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2009-04-08 | — | — | CN | disclosed |
| CN-101054345-A | Novel bensophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2007-10-17 | — | — | CN | disclosed |
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SHUNICHI SHIOZAWA (JP) | 2005-05-26 | — | — | US | disclosed |
| CN-1602291-A | Novel benzophenone derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2005-03-30 | — | — | CN | disclosed |
| EP-1445249-A1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SP1, AP1G1, JUN | FOS 163/4885JUN 3/4885NR1H4 1106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.