Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29680425 | 0.82 | MET (0.38) | TRPA1 | |
| SCHEMBL31281958 | 0.80 | — | — | |
| SCHEMBL19641545 | 0.78 | PARP1 (0.33) | — | |
| SCHEMBL31680206 | 0.78 | PARP1 (0.33) | — | |
| SCHEMBL29080089 | 0.77 | — | — | |
| SCHEMBL31048910 | 0.76 | — | — | |
| SCHEMBL29080149 | 0.76 | — | — | |
| SCHEMBL190598 | 0.76 | NCEH1 (0.47) | NCEH1 | |
| SCHEMBL16717453 | 0.76 | HTR2A (0.38) | TRPA1 | |
| SCHEMBL17200284 | 0.74 | SLC6A4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4262807-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022132200-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-06-23 | — | — | WO | disclosed |