SCHEMBL190598

SCHEMBL190598

CC(C)[Si](Oc1ccc2cc(Br)ccc2c1)(C(C)C)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 1/20 0.47
CYP2A6 P11509 1/20 0.42
LMNA P02545 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAPT P10636 4/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
KDM1A O60341 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
CYP3A4 P08684 3/20 0.38
HTT P42858 2/20 0.38
THRB P10828 1/20 0.38
FLT3 P36888 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL481885 0.82 MAPT (0.37) CYP2A6LMNAMAPTMEN1KMT2A
SCHEMBL31670075 0.81 CYP2A6 (0.52) CYP2A6KDM4ECYP1A2NPC1RAB9A
SCHEMBL1877066 0.79 MAOB (0.42) LMNAL3MBTL1MAPTKMT2AKDM4E
SCHEMBL15298750 0.79 CYP1A2 (0.50) CYP2A6LMNAKDM4EALDH1A1FLT3
SCHEMBL8171076 0.79 NCEH1 (0.47) NCEH1CYP2A6LMNAL3MBTL1MAPT
SCHEMBL13347413 0.76 CHRNA7 (0.42) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL15280333 0.76 CYP1A2 (0.50) CYP2A6LMNAMAPTMEN1KMT2A
SCHEMBL29680237 0.76 TRPA1 (0.31) NCEH1
SCHEMBL3138547 0.75 NCEH1 (0.56) NCEH1CYP2A6LMNAL3MBTL1MAPT
SCHEMBL17205115 0.74 HAO1 (0.44) LMNAL3MBTL1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9896587-B2 Planarizing agents and devices NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-02-20 US disclosed
US-9896587-B2 Planarizing agents and devices NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-02-20 US disclosed
US-9045683-B2 Polymerizable compounds and use thereof in liquid crystal displays MERCK PATENT GMBH (DE) 2015-06-02 US disclosed
US-9045683-B2 Polymerizable compounds and use thereof in liquid crystal displays MERCK PATENT GMBH (DE) 2015-06-02 US disclosed
US-9045683-B2 Polymerizable compounds and use thereof in liquid crystal displays MERCK PATENT GMBH (DE) 2015-06-02 US disclosed
US-20140299858-A1 PLANARIZING AGENTS AND DEVICES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-09 US disclosed
US-20140299858-A1 PLANARIZING AGENTS AND DEVICES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-09 US disclosed
US-20140299858-A1 PLANARIZING AGENTS AND DEVICES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-09 US disclosed
EP-2585555-B1 POLYMERIZIBLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2014-07-30 EP disclosed
EP-2585555-B1 POLYMERIZIBLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2014-07-30 EP disclosed
US-20120277367-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2012-11-01 US disclosed
US-20120277367-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2012-11-01 US disclosed
US-8187501-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2012-05-29 US disclosed
US-8187501-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2012-05-29 US disclosed
EP-2250207-B1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS INC (US) 2012-01-04 EP disclosed
WO-2011160765-A1 POLYMERIZIBLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-12-29 WO disclosed
EP-2250207-A1 PLANARIZING AGENTS AND DEVICES Plextronics, Inc. (US) 2010-11-17 EP disclosed
US-20100072462-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2010-03-25 US disclosed
US-20100072462-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2010-03-25 US disclosed
WO-2009111339-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. (US) 2009-09-11 WO disclosed