Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 13/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL29680369 | 0.96 | KDM5B (0.51) | KDM5BAKT1AKT2PIK3CAMTOR | |
| SCHEMBL29680588 | 0.84 | KDM4E (0.46) | KDM5BRAD52PIK3CAMTOR | |
| SCHEMBL29680888 | 0.83 | AKT1 (0.49) | AKT1AKT2RAD52 | |
| SCHEMBL29680774 | 0.83 | KDM4E (0.45) | KDM5BRAD52PIK3CAMTOR | |
| SCHEMBL29680625 | 0.83 | KDM4E (0.48) | KDM5BRAD52PIK3CAMTOR | |
| SCHEMBL29680767 | 0.80 | KDM5B (0.42) | KDM5BRAD52PIK3CAMTOR | |
| Oxalic Acid SCHEMBL29680932 | 0.79 | KDM4E (0.42) | KDM5BPIK3CAMTOR | |
| Oxalic Acid SCHEMBL29680443 | 0.79 | AKT1 (0.46) | KDM5BAKT1AKT2RAD52PIK3CA | |
| SCHEMBL29680354 | 0.79 | AKT1 (0.48) | AKT1AKT2RAD52PIK3CAMTOR | |
| Oxalic Acid SCHEMBL29680471 | 0.79 | KDM4E (0.45) | KDM5BPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263539-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2023-10-25 | — | — | EP | claimed |
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | claimed |
| EP-4263539-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |