Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 12/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | MTOR | P42345 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24528661 | 0.85 | RAD52 (0.36) | KDM4EALDH1A1MAPTMAPK1RAD52 | |
| SCHEMBL29680708 | 0.84 | GSK3B (0.41) | PIK3CAMTORKDM4EMEN1ALDH1A1 | |
| SCHEMBL29680812 | 0.83 | GSK3B (0.40) | PIK3CAMTORKDM4EMEN1ALDH1A1 | |
| SCHEMBL29680973 | 0.83 | KDM4E (0.41) | PIK3CAMTORKDM4EMEN1ALDH1A1 | |
| SCHEMBL24528648 | 0.82 | RAD52 (0.37) | KDM4EALDH1A1MAPTMAPK1RAD52 | |
| SCHEMBL29680554 | 0.82 | RAD52 (0.37) | KDM4EALDH1A1MAPTMAPK1RAD52 | |
| SCHEMBL24528690 | 0.82 | TLR9 (0.41) | KDM4EALDH1A1MAPTMAPK1RAD52 | |
| SCHEMBL29680640 | 0.80 | KDM5B (0.48) | KDM5BPIK3CAMTORRAD52 | |
| SCHEMBL24528649 | 0.78 | RAD52 (0.34) | KDM4EALDH1A1MAPTMAPK1RAD52 | |
| SCHEMBL24528685 | 0.78 | KDM4E (0.40) | PIK3CAMTORKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263539-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |