Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | AKT2 | P31751 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 7/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL29680443 | 0.96 | AKT1 (0.46) | AKT1AKT2RAD52TLR9POLB | |
| SCHEMBL29680730 | 0.90 | AKT1 (0.49) | AKT1AKT2RAD52CACNA1G | |
| SCHEMBL29680354 | 0.87 | AKT1 (0.48) | AKT1AKT2RAD52TLR9POLB | |
| SCHEMBL29680827 | 0.86 | AKT1 (0.49) | AKT1AKT2RAD52CACNA1G | |
| Oxalic Acid SCHEMBL29680612 | 0.86 | AKT1 (0.46) | AKT1AKT2RAD52POLBHPGD | |
| SCHEMBL29680379 | 0.85 | AKT1 (0.37) | AKT1AKT2RAD52TLR9POLB | |
| Oxalic Acid SCHEMBL29680295 | 0.84 | AKT1 (0.46) | AKT1AKT2RAD52TLR9POLB | |
| SCHEMBL29680640 | 0.83 | KDM5B (0.48) | AKT1AKT2RAD52 | |
| SCHEMBL29680618 | 0.83 | RAD52 (0.40) | RAD52TLR9POLBHPGD | |
| Oxalic Acid SCHEMBL29680370 | 0.83 | AKT1 (0.46) | AKT1AKT2RAD52CACNA1GHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263539-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2023-10-25 | — | — | EP | claimed |
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | claimed |
| EP-4263539-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |