Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24528661 | 0.86 | RAD52 (0.36) | TLR9AVPR1ARAD52NPC1RAB9A | |
| SCHEMBL24528639 | 0.84 | ATM (0.37) | TLR9KDM4EALDH1A1 | |
| SCHEMBL29680554 | 0.83 | RAD52 (0.37) | TLR9AVPR1ARAD52NPC1RAB9A | |
| SCHEMBL24528648 | 0.83 | RAD52 (0.37) | TLR9AVPR1ARAD52NPC1RAB9A | |
| SCHEMBL29680767 | 0.82 | KDM5B (0.42) | RAD52MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL24528649 | 0.79 | RAD52 (0.34) | TLR9AVPR1ARAD52NPC1RAB9A | |
| SCHEMBL24528686 | 0.78 | RAB9A (0.35) | TLR9AVPR1ANPC1RAB9AMAPT | |
| SCHEMBL24528685 | 0.75 | KDM4E (0.40) | TLR9RAD52NPC1RAB9AMAPT | |
| SCHEMBL29681200 | 0.75 | KDM4E (0.40) | TLR9RAD52NPC1RAB9AMAPT | |
| SCHEMBL24528659 | 0.74 | ALDH1A1 (0.36) | RAD52NPC1RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |