Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | AKT2 | P31751 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 11/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29680730 | 0.96 | AKT1 (0.49) | AKT1AKT2CACNA1GRAD52 | |
| Oxalic Acid SCHEMBL29680370 | 0.96 | AKT1 (0.46) | AKT1AKT2CACNA1GRAD52 | |
| Oxalic Acid SCHEMBL29680612 | 0.92 | AKT1 (0.46) | AKT1AKT2CACNA1GRAD52 | |
| SCHEMBL29680888 | 0.86 | AKT1 (0.49) | AKT1AKT2CACNA1GRAD52 | |
| SCHEMBL29680230 | 0.83 | TMEM97 (0.43) | CACNA1GRAD52 | |
| Oxalic Acid SCHEMBL29680443 | 0.82 | AKT1 (0.46) | AKT1AKT2CACNA1GRAD52 | |
| SCHEMBL24528667 | 0.80 | ALDH1A1 (0.36) | CACNA1GRAD52 | |
| SCHEMBL29681267 | 0.80 | ALDH1A1 (0.36) | CACNA1GRAD52 | |
| SCHEMBL29680649 | 0.79 | TMEM97 (0.43) | RAD52 | |
| Oxalic Acid SCHEMBL29680659 | 0.79 | ATM (0.41) | CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263539-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2023-10-25 | — | — | EP | claimed |
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | claimed |
| EP-4263539-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |