Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23617121 | 1.00 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2SLC22A12RAD51 | |
| SCHEMBL19783105 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31278153 | 0.77 | — | — | |
| SCHEMBL23235054 | 0.77 | — | — | |
| SCHEMBL20197189 | 0.76 | HDAC8 (0.36) | LOXL2LOXNOS3NOS2 | |
| SCHEMBL16548463 | 0.76 | UHRF1 (0.45) | KDM4EALDH1A1SMN1; SMN2SYKNOS3 | |
| SCHEMBL25203651 | 0.74 | LOXL2 (0.59) | LOXL2LOXSYK | |
| SCHEMBL26192789 | 0.74 | NOS3 (0.50) | KDM4ELOXL2LOXNOS3NOS2 | |
| SCHEMBL31706588 | 0.74 | SIRT2 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL29898951 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127756-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2022-06-23 | — | — | WO | disclosed |