Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 7/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31127539 | 0.90 | PRMT1 (0.55) | ACEOPRM1OPRD1PRMT1ECE1 | |
| SCHEMBL30502979 | 0.89 | OPRM1 (0.61) | ACEOPRM1OPRD1ECE1 | |
| SCHEMBL9753233 | 0.88 | PRMT1 (0.56) | ACEOPRM1OPRD1PRMT1KDM4E | |
| SCHEMBL9753236 | 0.88 | PRMT1 (0.56) | ACEOPRM1OPRD1PRMT1KDM4E | |
| SCHEMBL30255956 | 0.88 | ACE (0.58) | ACEOPRM1OPRD1PRMT1KDM4E | |
| SCHEMBL30465846 | 0.88 | ACE (0.62) | ACEKDM4EMEN1LMNAMPO | |
| SCHEMBL30502988 | 0.88 | OPRM1 (0.64) | ACEOPRM1OPRD1ECE1 | |
| SCHEMBL30052764 | 0.88 | KDM4E (0.62) | ACEOPRM1OPRD1KDM4EMEN1 | |
| SCHEMBL31256945 | 0.86 | OPRD1 (0.71) | OPRM1OPRD1 | |
| SCHEMBL30605164 | 0.86 | ACE (0.59) | ACEOPRM1OPRD1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3996815-A2 | HIV BINDING AGENTS | LAUSANNE UNIVERSITY HOSPITAL (CH) | 2022-05-18 | — | — | EP | disclosed |